Publish faster. Stay audit-ready.
AI-assisted meta-analysis from question to manuscript. Axelium combines intelligent screening and extraction with R-based statistics — so your team delivers rigorous reviews in days, not months.
One pipeline. Every stage. A living loop.
Ten stages from research question to published manuscript, with sign-off gates at the milestones that matter and a living-review loop wrapped around the whole pipeline. Everything on one platform — no stitched-together exports, no copy-paste between tools.
Every stage, integrated. Then kept current.
From research question to published manuscript to a living evidence base — every stage integrated, auditable, and designed for teams that demand rigour.
Seen enough? — free tier runs the full pipeline on one real review, end to end.
Every search becomes a PRISMA flow.
The diagram updates itself as records move through the pipeline. Identification, screening, eligibility, included — with every exclusion category linked to the studies it removed. Export as Word, PDF, or a publication-ready figure with one click.
- Counts trace to the underlying studies — every number in the diagram is a live link in the app.
- Conforms to PRISMA 2020. Every reviewer decision is timestamped and reproducible.
- Living reviews keep the diagram current — the version in your manuscript matches the one in the app.
Each exclusion category traces to the studies it removed. Click any number in the live app to see the underlying list.
Detect publication bias at a glance.
A funnel plot puts every included study on a single chart — precision on the vertical axis, effect size on the horizontal. Asymmetry is the visual fingerprint of missing small negative trials. The plot is paired with Egger's and Begg's tests so a reviewer can quote both the picture and the number.
- HTA submissions require a publication-bias appraisal whenever ten or more studies are pooled — the funnel plot is the expected first artefact.
- Contour-enhanced and trim-and-fill variants are one click away, with the statistical tests and a plain-language interpretation alongside the figure.
- Every plot is regenerated when new evidence arrives — the figure in your dossier matches the live evidence base on the day you submit.
Every reviewer-facing tool implements a published methodological standard. The references below are the ones our automation answers to — not in spirit, in code.
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
Page MJ, McKenzie JE, Bossuyt PM, et al.
BMJ 2021;372:n71
Cochrane Handbook for Systematic Reviews of Interventions
Higgins JPT, Thomas J, Chandler J, et al.
Version 6.5, Cochrane
RoB 2: a revised tool for assessing risk of bias in randomised trials
Sterne JAC, Savović J, Page MJ, et al.
BMJ 2019;366:l4898
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guyatt GH, Oxman AD, Vist GE, et al.
BMJ 2008;336:924
Drops into your existing review workflow.
Bring your references in, send your manuscript out — Axelium connects to the databases, reference managers, and authoring tools you already use.
Import RIS or BibTeX from EndNote, Zotero, Mendeley, Embase, and Web of Science.
Export to RevMan 5 (.rm5) for risk-of-bias and final authoring.
PubMed, ClinicalTrials.gov, EuropePMC, OpenAlex, CENTRAL, MAUDE, ERIC.
Walk references, citers, and recommendations via Semantic Scholar.
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