Question 1

What types of reviews does Axelium support?

Accepted Answer

Axelium supports intervention reviews (PICO), prevalence and risk-factor reviews (PEO), and qualitative synthesis workflows. You can handle dichotomous, continuous, survival, and proportion-based outcomes in a single project.

Question 2

How does the AI extraction work?

Accepted Answer

Axelium uses AI models to read full-text PDFs and extract structured data fields you define (events, totals, means, hazard ratios, etc.). Every extracted value is linked to its source table or text snippet. You review and approve each value before it enters any analysis.

Question 3

Is the statistical analysis really running in my browser?

Accepted Answer

Axelium runs the R metafor package on a dedicated statistics server. The AI writes and executes R scripts on your behalf, giving you the full power of metafor without installing anything.

Question 4

Can I use Axelium for regulatory submissions?

Accepted Answer

Axelium is designed with audit-readiness in mind. Every screening decision, extraction, and configuration change is logged with timestamps. PRISMA flow diagrams are generated automatically, and you can export full audit trails for submission packages.

Question 5

How is Axelium different from Covidence or Rayyan?

Accepted Answer

Those tools primarily focus on screening. Axelium covers the entire workflow — from question design and search strategy through AI extraction, R-based meta-analysis, reporting, and living review updates. You don't need to stitch together multiple tools.

Question 6

Can I trust the AI extractions for publication?

Accepted Answer

Yes — with the same scrutiny you would apply to any reviewer. Axelium's AI suggests candidate extractions, but all values must be reviewed and approved before entering any analysis. Statistical calculations are handled by deterministic, tested code, not by the AI. Every extracted value links back to its source table or text in the PDF, so you can verify each data point before including it.

Feature	Manual workflows	Screening-only tools	Axelium
Structured PICO / PEO question builder
Database-ready search strategies
AI-assisted title/abstract screening
Full-text AI extraction (PDF to data)
R/metafor statistical engine
Forest plots, funnel plots & diagnostics
PRISMA flow diagrams
AI-assisted manuscript drafting
Living review automation
Full audit trail & traceability
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