Know the day the evidence turns against your drug. Before the committee does.
Your value story is judged against the whole treatment landscape — not the single comparator in your trial. Axelium builds the network meta-analysis behind that story and keeps it live: when a new competitor trial lands, it re-runs and shows you the shift, while there is still time to answer it.
Network meta-analysis · living reviews · deterministic statisticsFrom a one-off comparison to a standing early-warning system.
Same workflow, two states. Flip the switch to see what changes.
Live · re-runs weekly · signed each cycle
- Cadence
- Re-runs automatically on a schedule
- automatic
- Competitor readouts
- Flagged the day the trial is indexed
- same day
- Assessor critique
- Stress-tested against the same methods first
- pre-empted
- Every market
- One evidence spine, re-projected per country
- ×1 spine
Build the comparison once. Keep it live. Inspect everything.
Build the comparison once
- A systematic review and a network meta-analysis
- Anchored against every relevant comparator
- Defensible from the first submission
Re-runs on a schedule
- The whole pipeline re-runs on a cadence
- Flags when a new trial moves the result
- A signed record of what changed, each cycle
No black box
- Deterministic statistics — same inputs, same result
- Every estimate traces to its source study
- Change an assumption and re-run
Methods that stand up to the same scrutiny.
We reproduced a published meta-analysis: 3 of 4 endpoints within 6%.
One analyst rebuilt a peer-reviewed meta-analysis end to end in 2 days. Pooled estimates for three of four endpoints landed within 6% of the published values, and the case study explains the fourth. The statistics are deterministic: the same inputs always give the same result.
Read the case studyComparisons a committee will accept
Pairwise and network meta-analysis, plus population-adjusted indirect comparisons, with certainty grading — every step inspectable.
- Network meta-analysis
- MAIC
- STC
- ML-NMR
- Custom methods
- GRADE certainty
Turn a completed submission into a standing watch.
Pick your battleground
Choose a drug, an indication, and a country. We scope the evidence network that decides its value.
Map the network
Your position against the whole field, today — anchored where the evidence connects, flagged where it doesn’t.
Keep it live
When a competitor’s trial changes the picture, the review re-runs and shows you the shift — in time to respond.
The questions access teams actually ask.
“AI in a submission?”
The statistics are deterministic and reproducible. AI assists data extraction; it never touches the numbers a committee sees.
“Just another tracker?”
Trackers tell you a decision happened. Axelium rebuilds the comparison that drives yours — and keeps it current.
“Our data is confidential.”
Your data stays in your workspace. Every estimate is inspectable and traceable to its source.